Publications

Journal Articles:

  1. Mechanical wall stress and wall shear stress are associated with atherosclerosis development in non-calcified coronary segments, Tziotziou, A., E. Hartman, S.-A. Korteland, A. van der Lugt, A. F. W. van der Steen, J. Daemen, D. Bos, J. Wentzel, and A. C. Akyildiz, Atherosclerosis 387:117387, 2023.
  2. Serial RV Wall Stress Measurement: Association with Right Ventricular Function in Tetralogy of Fallot Patients, Minderhoud, S. C. S., A. Hirsch, F. Marin, I. Kardys, J. F. Rodriguez Matas, C. Chiastra, J. W. Roos-Hesselink, J. Wentzel, W. A. Helbing, and A. C. Akyildiz, Frontiers in Cardiovascular Medicine, doi: 10.3389/fcvm.2023.1256792, 2023.
  3. A tissue-engineered model of the atherosclerotic plaque cap: Toward understanding the role of microcalcifications in plaque rupture. Jansen, I., H. Crielaard, T. Wissing, C. Bouten, F. Gijsen, A. C. Akyildiz, E. Farrell, and K. van der Heiden. APL Bioengineering 7:036120, 2023.
  4. Cross‐Sectional Validation of a Novel Computed Tomography‐Based Carotid Mean Calcium Density Measurement. Cahalane, R., A. C. Akyildiz, M. Kavousi, M. W. Vernooij, M. K. Ikram, F. Gijsen, and D. Bos. Journal of the American Heart Association 0:e027866.
  5. Local characterization of collagen architecture and mechanical failure properties of fibrous plaque tissue of atherosclerotic human carotid arteries. Torun, S. G., P. de M. Munoz, H. Crielaard, H. J. M. Verhagen, G.-J. Kremers, A. F. W. van der Steen, and A. C. Akyildiz. Acta Biomaterialia 164:293–302, 2023.
  6. Tensile and Compressive Mechanical Behaviour of Human Blood Clot Analogues. Cahalane, R. M. E., J. J. de Vries, M. P. M. de Maat, K. van Gaalen, H. M. van Beusekom, A. van der Lugt, B. Fereidoonnezhad, A. C. Akyildiz, and F. J. H. Gijsen. Ann Biomed Eng 51:1759–1768, 2023.
  7. Intravascular optical coherence elastography. Wang, T., T. Pfeiffer, A. Akyildiz, H. M. M. van Beusekom, R. Huber, A. F. W. van der Steen, and G. van Soest. Biomed. Opt. Express, BOE 13:5418–5433, 2022.
  8. Morphological Subtypes of Intracranial Internal Carotid Artery Arteriosclerosis and the Risk of Stroke. van den Beukel, T. C., J. E. van der Toorn, M. W. Vernooij, M. Kavousi, A. C. Akyildiz, P. A. de Jong, A. van der Lugt, M. K. Ikram, and D. Bos. Stroke 53:1339–1347, 2022.
  9. Thrombus mechanics: How can we contribute to improve diagnostics and treatment? Migliavacca, F., G. Luraghi, A. C. Akyildiz, and F. J. H. Gijsen. Journal of Biomechanics 132:110935, 2022.
  10. Multicomponent material property characterization of atherosclerotic human carotid arteries through a Bayesian Optimization based inverse finite element approach. Guvenir Torun, S., H. M. Torun, H. H. G. Hansen, C. L. de Korte, A. F. W. van der Steen, F. J. H. Gijsen, and A. C. Akyildiz. Journal of the Mechanical Behavior of Biomedical Materials 126:104996, 2022.
  11. A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue. Crielaard, H., S. Guvenir Torun, T. B. Wissing, P. de Miguel Muñoz, G.-J. Kremers, F. J. H. Gijsen, K. Van Der Heiden, and A. C. Akyildiz. J Vis Exp, 2022.doi:10.3791/64334
  12. A review on the association of thrombus composition with mechanical and radiological imaging characteristics in acute ischemic stroke. Cahalane, R., N. Boodt, A. C. Akyildiz, J. Giezen, M. Mondeel, A. van der Lugt, H. Marquering, and F. Gijsen. Journal of Biomechanics 129:110816, 2021.
  13. In vitro and in silico modeling of endovascular stroke treatments for acute ischemic stroke. Luraghi, G., R. M. E. Cahalane, E. van de Ven, S. C. M. Overschie, F. J. H. Gijsen, and A. C. Akyildiz. Journal of Biomechanics 127:110693, 2021.
  14. Seven-year clinical and mechanical follow-up of a Tetralogy of Fallot patient with severe pulmonary regurgitation. Minderhoud, S. C. S., A. C. Akyildiz, A. Hirsch, and W. A. Helbing. European Heart Journal – Cardiovascular Imaging, 2021.doi:10.1093/ehjci/jeab167
  15. Mechanical Characterization of Thrombi Retrieved With Endovascular Thrombectomy in Patients With Acute Ischemic Stroke. Boodt, N., P. R. W. Snouckaert van Schauburg, H. M. Hund, B. Fereidoonnezhad, J. P. McGarry, A. C. Akyildiz, A. C. G. M. van Es, S. F. De Meyer, D. W. J. Dippel, H. F. Lingsma, H. M. M. van Beusekom, A. van der Lugt, and F. J. H. Gijsen. Stroke 52:2510–2517, 2021.
  16. Morphometric and Mechanical Analyses of Calcifications and Fibrous Plaque Tissue in Carotid Arteries for Plaque Rupture Risk Assessment. Gijsen, F. J. H., B. Vis, H. E. Barrett, A. A. Zadpoor, H. J. Verhagen, D. Bos, A. F. W. van der Steen, and A. C. Akyildiz. IEEE Transactions on Biomedical Engineering 68:1429–1438, 2021.
  17. Multicomponent Mechanical Characterization of Atherosclerotic Human Coronary Arteries: An Experimental and Computational Hybrid Approach. Guvenir Torun, S., H. M. Torun, H. H. G. Hansen, G. Gandini, I. Berselli, V. Codazzi, C. L. de Korte, A. F. W. van der Steen, F. Migliavacca, C. Chiastra, and A. C. Akyildiz. Frontiers in Physiology 12:1480, 2021.
  18. Colocalization of Intracoronary Lipid-Rich Plaques and Calcifications. Hartman, E. M. J., A. Hoogendoorn, A. C. Akyildiz, A.-S. Schuurman, A. F. W. van der Steen, E. Boersma, J. J. Wentzel, and J. Daemen. JACC: Cardiovascular Imaging 13:1627–1628, 2020.
  19. Calcifications in atherosclerotic plaques and impact on plaque biomechanics. Barrett, H. E., K. Van der Heiden, E. Farrell, F. J. H. Gijsen, and A. C. Akyildiz. Journal of Biomechanics 87:1–12, 2019.
  20. Intima heterogeneity in stress assessment of atherosclerotic plaques. Akyildiz, A. C., L. Speelman, B. van Velzen, R. R. F. Stevens, A. F. W. van der Steen, W. Huberts, and F. J. H. Gijsen. Interface Focus. 8:20170008, 2018.
  21. In situ mechanical characterization of multilayer soft tissue using ultrasound imaging. Dargar, S., A. C. Akyildiz, and S. De. IEEE Trans Biomed Eng 64:2595–2606, 2017.
  22. 3D Fiber Orientation in Atherosclerotic Carotid Plaques. Akyildiz, A. C., C.-K. Chai, C. W. J. Oomens, A. van der Lugt, F. P. T. Baaijens, G. J. Strijkers, and F. J. H. Gijsen. Journal of Structural Biology 200:28–35, 2017.
  23. Energy Dissipation in Ex-Vivo Porcine Liver during Electrosurgery. Karaki, W., A. C. Akyildiz, S. De, and D.-A. Borca-Tasciuc. IEEE Trans Biomed Eng 64:1211–1217, 2017.
  24. The effects of plaque morphology and material properties on peak cap stress in human coronary arteries. Akyildiz, A. C., L. Speelman, H. A. Nieuwstadt, H. van Brummelen, R. Virmani, A. van der Lugt, A. F. W. van der Steen, J. J. Wentzel, and F. J. H. Gijsen. Computer Methods in Biomechanics and Biomedical Engineering 19:771–779, 2016.
  25. A Framework for Local Mechanical Characterization of Atherosclerotic Plaques: Combination of Ultrasound Displacement Imaging and Inverse Finite Element Analysis. Akyildiz, A. C., H. H. G. Hansen, H. A. Nieuwstadt, L. Speelman, C. L. De Korte, A. F. W. van der Steen, and F. J. H. Gijsen. Ann Biomed Eng 44:968–979, 2016.
  26. Local anisotropic mechanical properties of human carotid atherosclerotic plaques – Characterisation by micro-indentation and inverse finite element analysis. Chai, C.-K., A. C. Akyildiz, L. Speelman, F. J. H. Gijsen, C. W. J. Oomens, M. R. H. M. van Sambeek, A. van der Lugt, and F. P. T. Baaijens. Journal of the Mechanical Behavior of Biomedical Materials 43:59–68, 2015.
  27. Uniaxial tensile testing approaches for characterisation of atherosclerotic plaques. Walsh, M. T., E. M. Cunnane, J. J. Mulvihill, A. C. Akyildiz, F. J. H. Gijsen, and G. A. Holzapfel. Journal of Biomechanics 47:793–804, 2014.
  28. Mechanical properties of human atherosclerotic intima tissue. Akyildiz, A. C., L. Speelman, and F. J. H. Gijsen. Journal of Biomechanics 47:773–783, 2014.
  29. Local axial compressive mechanical properties of human carotid atherosclerotic plaques—characterisation by indentation test and inverse finite element analysis. Chai, C.-K., A. C. Akyildiz, L. Speelman, F. J. H. Gijsen, C. W. J. Oomens, M. R. H. M. van Sambeek, A. van der Lugt, and F. P. T. Baaijens. Journal of Biomechanics 46:1759–1766, 2013.
  30. The influence of axial image resolution on atherosclerotic plaque stress computations. Nieuwstadt, H. A., A. C. Akyildiz, L. Speelman, R. Virmani, A. van der Lugt, A. F. W. van der Steen, J. J. Wentzel, and F. J. H. Gijsen. Journal of Biomechanics 46:689–695, 2013.
  31. Initial stress in biomechanical models of atherosclerotic plaques. Speelman, L., A. C. Akyildiz, B. den Adel, J. J. Wentzel, A. F. W. van der Steen, R. Virmani, L. van der Weerd, J. W. Jukema, R. E. Poelmann, E. H. van Brummelen, and F. J. H. Gijsen. Journal of Biomechanics 44:2376–2382, 2011.
  32. Effects of intima stiffness and plaque morphology on peak cap stress. Akyildiz, A. C., L. Speelman, H. van Brummelen, M. A. Gutiérrez, R. Virmani, A. van der Lugt, A. F. van der Steen, J. J. Wentzel, and F. J. Gijsen. BioMed Eng OnLine 10:25, 2011.